Field Guide
Micronutrient Deficiencies
Sub-clinical shortfalls in specific vitamins and minerals (vitamin D, B12, iron, magnesium, zinc, iodine) drive fatigue, mood, and cognitive symptoms — and are among the most fixable root causes.
Micronutrients are the spark plugs of your metabolism — too small to see, but every process misfires without them.
In plain English
Vitamins and minerals are cofactors for thousands of enzymatic reactions. Sub-clinical shortfalls — below optimal but above frank deficiency — drive fatigue, mood, sleep, and cognitive symptoms and often go undetected on standard labs.
The most common shortfalls: vitamin D, B12, iron/ferritin, magnesium, zinc, iodine, selenium, and omega-3s. Causes range from restrictive diets to gut malabsorption, medications (PPIs, metformin, oral contraceptives), and higher demand from stress or infection.
These are among the most fixable root causes — but 'fixable' means testing to target the actual gap, then re-testing, not blanket supplementation.
Where you feel it
The step-by-step
- 1Reduced intake or absorption
Diet, gut issues, low stomach acid, or medications limit nutrient uptake.
- 2Increased demand
Chronic stress, infection, pregnancy, or intense training raise the need.
- 3Sub-clinical shortfall
Levels drop into the 'suboptimal but not deficient' range on standard labs.
- 4Enzymatic slowdown
Thousands of reactions run at reduced capacity — driving diffuse symptoms.
Symptoms, causes & labs
- Fatigue disproportionate to lifestyle
- Restless legs, muscle cramps (magnesium)
- Cracks at mouth corners (B2/iron)
- Frequent infections, slow wound healing (zinc, D)
- Malabsorption (gut dysbiosis, low stomach acid)
- Restrictive diets, ultra-processed food
- Medications (PPIs, metformin, oral contraceptives)
- 25-OH vitamin D, B12 / MMA, folate
- Ferritin and full iron studies
- RBC magnesium, zinc, selenium, iodine
Common lifestyle changes that help
These are the foundational shifts most often used alongside clinical care for this pattern. Start with one; layer in the next only when the first feels automatic. Discuss anything major with your practitioner.
- Eat 4–5+ servings of vegetables and fruit daily, varying the colors
- Get 15–20 minutes of midday sun on skin (or supplement vitamin D)
- Include iron-rich foods (red meat, liver, lentils) with vitamin C for absorption
- Vegans/vegetarians: supplement B12, and consider iron, zinc, omega-3 (algae)
- Cook in cast iron; use mineral-rich sea salt
Red flags — don't wait
- Severe fatigue with pallor and shortness of breath (rule out severe anemia)
- New numbness or tingling in hands/feet (possible B12 deficiency)
- Bone pain in a child or adult with severe vitamin D deficiency
Supportive habits to discuss
- Test before supplementing — especially iron and iodine
- Optimal ranges differ from 'normal' — work with a practitioner familiar with functional ranges
- Address root cause of malabsorption — supplementing over a leaky gut is short-term
Is this pattern showing up in your body?
Take our physician-designed assessment — 8 minutes, 80 questions across 25 root-cause categories.
Related categories
Medical disclaimer
This page is educational only. It is NOT medical advice, diagnosis, or treatment. Do not self-treat based on the information here. If you have symptoms, consult a licensed healthcare professional.